Human Data Trials™
Revalia Bio partners with research teams to answer questions at critical decision points across drug and device development programs.
We conduct structured organ-level research studies with revived donated human organs. These studies integrate multiple biological signals into a unified translational framework.
Revalia's studies generate human biological data that can inform development decisions, including:
Our studies can be conducted as focused investigations addressing specific development questions or broader collaborations that generate human biological datasets.
At the heart of these studies is the human data stack, a data architecture that integrates multiple biological data layers to generate human biological data with clinical context.
This architecture connects patient information, revived donated human organs, and advanced experimental models into a unified translational system.
Together, these layers generate high-fidelity biological data that can be translated into decision-grade insights.
Patient context and samples provide essential information for interpreting biological signals and therapeutic response.
Perfused donated organs enable functional and structural data generation across intact human organ systems, allowing researchers to study biology in a way that traditional models cannot replicate.
Tissue samples enable cellular and molecular analysis across multiple timepoints, revealing how tissues respond to therapeutic intervention.
Advanced experimental models enable high-resolution evaluation of drug response and biological mechanisms.
Revalia studies can support research teams at multiple stages of development, from discovery and translational research through clinical programs. By generating organ-level human biological data, we help teams interpret existing findings and strengthen development decisions.
Traditional drug and device development models provide critical insight, but they do not fully replicate human organ biology. Differences in expression, metabolism, and immune response can influence safety and performance outcomes in ways that are not always visible in animal systems.
By adding organ-level human insight, researchers can better evaluate safety, assess performance characteristics, and accelerate programs across the life sciences ecosystem.
Supporting each study is Revalia's infrastructure, which integrates ethical organ stewardship, standardized experimental workflows, and multi-modal data capture.
This foundation ensures that each study is conducted with scientific rigor and regulatory awareness. It supports repeatable integration into development programs.
Using our trusted nationwide network of organ procurement organizations, we can rapidly access viable human organs and tissues for research. These transplant-grade-quality organs represent diverse patient profiles and support both observational and interventional studies.
Organs are perfused using advanced proprietary hardware in our 8,000 SF facility in New Haven. This 24/7 "organ ICU" is designed for extended organ longevity and is staffed by a dedicated transplant surgeon and perfusion specialist.
Revalia's human data stack captures patient-level context from real donated organs—turning complex histories into decision-grade insights for translational research.
Our intelligent software suite powers next-generation human trials by guiding real-time data capture, surfacing insights, and connecting researchers and developers within a single system.
Revalia collaborates with biopharma and translational researchers to translate human biological data into actionable decisions, ranging from trial design and adaptation to regulatory and IND-readiness guidance.
Work with Revalia to identify the specific safety, efficacy, or performance questions to be evaluated.
Collaborate on experimental design and establish measurable endpoints aligned to your development goals.
Through our Organ Access Network, appropriate donors are screened and prepared to ensure integrity and scientific rigor.
Trials are conducted with clinical precision, capturing high-fidelity organ-level data.
Biological signals are collected across molecular, imaging, histopathological, and functional outputs.
Data is synthesized into structured insights aligned with your development milestones.
Use the results to refine, advance, or reprioritize your program with greater confidence.
Ready to accelerate your next program? Schedule a meeting with our team to explore how Human Data Trials can transform your pipeline.